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Thalamic hypogeusiamay be associated with a cheiro-oral syndrome (Sanchez-Juan and Combarros, 2001). It is also very dif?cult to accurately quantify the prevalence of thissyndrome as the recessive nature of the mutations means that MAP may be under-diagnosed in apparently sporadic cases, and it might actually be much more commonthan the currently reported incidence of 0.4–3 % [ 17] It is also very dif?cult to accurately quantify the prevalence of thissyndrome as the recessive nature of the mutations means that MAP may be under-diagnosed in apparently sporadic cases, and it might actually be much more commonthan the currently reported incidence of 0.4–3 % [ 17].
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